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Q.et al (2012)

Cerebrospinal fluid levels of free 3-nitrotyrosine are not elevated in the majority of patients with amyotrophic lateral sclerosis or Alzheimers disease

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Very small pieces of cartilage are ground off the patella vs femur (kneecap vs thigh bone) joint over the years due to uneven wearing patterns on a smaller area of the cartilage of either bone
FEBS Lett 580:10231035
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