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To further scrutinize the substrate specificity of Ubp2 and Ubp3, we investigated the linkage of uS10 in the ubp2ubp3 double deletion mutant (Fig

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the CNS pathology is one of a neurodegenerative disorder, such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), cerebrovascular accidents (CVA: ischemic stroke, intracerebral hemorrhage (ICH) or subarachnoid hemorrhage (SAH)), vascular-related dementia, brain trauma (traumatic brain injury), spinal cord injury, alcoholism, Prion diseases: Creutzfeldt- Jakob disease (CJD), bovine spongiform encephalopathy (BSE)

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Ethanol/acetaldehyde exposure Ethanol and acetaldehyde exposure are pharmacological interventions that mimic the cardioprotective effects of IPC, although the effects are limited at lower doses

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