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Description
Each monomer of a cytosolic GST is composed of an N-terminal domain (domain I) and C-terminal domain (domain II)
GC1 is upregulated at both the mRNA and protein levels in colorectal [109], gallbladder [110], osteosarcoma [111], and pancreatic cancer [109,112]
Furthermore, we found that the longer the alkyl chain of R1 group is, the better its inhibition potency is
This multifactorial assault on glutathione homeostasis creates a compelling rationale for exogenous support, particularly through delivery methods that ensure reliable tissue concentrations
It remains a research compound, not an approved or proven fat-loss treatment
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