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Tryptophan metabolites in fibrosis regulation Tryptophan metabolism plays a complex, context-dependent role in pulmonary fibrosis, influencing ECM deposition, fibroblast activation, and immune responses

Factors Affecting Glutathione Levels Despite its importance, glutathione levels can be compromised due to various factors, including: Aging : Naturally, glutathione levels decline as we age, leading to increased oxidative stress and susceptibility to diseases

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MDR, which describes the development of resistance to multiple therapeutic agents (119), can develop due to inherent cellular characteristics or be acquired during or after chemotherapy (120, 121)

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