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Some disorders of intracellular cobalamin metabolism (cblC, cblD-MMA/Hcy, cblF, and cblJ) do not only compromise the synthesis of methylcobalamin, but also the synthesis of adenosylcobalamin, cofactor of the enzyme methylmalonyl-CoA mutase, leading to elevated concentrations of both tHcy and methylmalonic acid (MMA)

Your spinal cord is a very important bundle of nerves that runs from your brain to your lower back

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Buers, et al

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Last updated: March 9, 2026 If you are considering B12 injections this spring whether as part of a pre-summer wellness refresh or to address persistent fatigue understanding the risks is just as important as knowing the benefits
