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In U20 APO/GSH/GS-PAP , this tryptophan residue is buried (accessible surface area (ASA) of 4 2 ), making the H-site quite deep (Supplementary Figure S6)

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Furthermore, L-SOD could also reduce OxS to intestinal barrier, thereby ameliorating the vicious circle between hyperglycemia and the oxidative damage 751

Additionally, LEPs and contact heatevoked potentials, which activate nociceptors through radiant and conductive heat, respectively, have been increasingly utilized in the diagnosis of neuropathic pain, especially in cases of small fiber neuropathy
