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Importantly, CQ inhibits the proteasome in leukemia and myeloma cells, but is not effective on normal cells (Mao et al., 2009), indicating that it has selective antitumor activity

The overall structure of Lb TDC is shown in Fig

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D., Weigel C., et al., Targeting Defective Sphingosine Kinase 1 in NiemannPick Type C Disease With an Activator Mitigates Cholesterol Accumulation, Journal of Biological Chemistry 295, no

Change history 10 February 2021 This Editorial makes references to some papers

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