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Enzyme replacement treatment (ERT) with recombinant human -Gal A decreased the Gb3 accumulation and oxidative stress, which resulted in amelioration of the deformed cellular structure of the GLA-mutant kidney organoids

Data are shown as the median SEM of 3 independent experiments

doi: 10.12688/f1000research.18411.1 26 OggerPPByrneAJ

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These culture conditions generated 41,392 colonies, which were tested by MALDITOF

All these three substances have been tested in animal models showing protective effects on kidneys and intestine and heart
