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Recent studies have demonstrated that BMSC-Exos can promote neurological recovery in ASCI by inhibiting ferroptosis through the Nrf2/GTP cyclohydrolase I (GCH1)/5,6,7,8-tetrahydrobiopterin (BH4) signaling axis, reducing oxidative stress, and enhancing the expression of ferroptosis suppressors [146]

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Higher is not always better: excess free copper can be pro-oxidant

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These studies all showed that GLP-/GIP dual agonists had similar effects on lipid metabolism to GLP-1, and even had better effects on lipid reduction and weight loss

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In Experiment 1, oocyte viability, early apoptosis, mortality, oxidative status, the mitochondrial membrane potential and distribution, DNA fragmentation, maturation, fertilization, embryo development rates, blastocyst quality and cumulus cell activity were analyzed by factorial ANOVA followed by the Bonferroni post hoc correction

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