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Note: Values under 10 units are hard to measure accurately for micro-dosing

35, in the keto form of curcumin, the heptadienone linkage between the two methoxyphenol rings contains a highly activated carbon atom

However, getting the dose right still matters for optimal results

We aim to validate this logic through GPX4 protein knockdown and experiments with well-established ferroptosis inducers and inhibitors to demonstrate the cause-and-effect relationship

Although well-characterized as an antifungal drug target in microorganisms, the roles of human CYP51A1 in development, cell death regulation, and disease pathogenesis remain underexplored

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