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Data Availability Data applicability statement is not applicable as this is a review article that is based on existing literature and we have not collected any data for this purpose

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Tools include: Therapy Acupuncture, massage, and bodywork Deep breathing Meditation Exercise Spending time in nature Unplugging from technology Yoga and tai chi And more Reduce Oxidative Stress We want to both reduce and combat oxidative stress with antioxidants (more on that soon)

4-HNE can also be generated through both enzymatic and non-enzymatic reactions from the breakdown of -6 PUFAs

In DR, DNMT1 levels are significantly elevated in mitochondria, leading to mtDNA hypermethylation, which impairs transcription and disrupts mitochondrial function, including the electron transport chain (ETC) and overall mitochondrial homeostasis (67)

A curious connection: teasing apart the link between gut microbes and lung disease