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Diabetes 66(11):2903-14 2017 PMC5652606 Perreault L, Pan Q, Aroda VR, Barrett-Connor E, Dabelea D, Dagogo-Jack S, Hamman RF, Kahn SE, Mather KJ, Knowler WC, Diabetes Prevention Program Research Group

TMAO may negatively affect insulin signalling by reducing the mRNA levels of key insulin pathway components in high-fat diet-fed mice

At the same time, it is important to remark that the finding of lower C2 as risk factor for depression is highly consistent with data from other studies using clinical samples, animal models and genomic data [32, 65]

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Correcting magnesium deficiency may improve Hashimotos symptoms (24,25)
