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As a glutaminase inhibitor, CB-839 is highly sensitive to esophageal squamous cell carcinoma (ESCC), which is highly dependent on glutamine metabolism for energy, providing a new possibility for the treatment of ESCC [69]

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Additional assessment of nerve-specific growth factor content including NGF, ciliary neurotrophic factor (CNTF), brain-derived neurotrophic factor (BDNF), and NT-3 was performed by ELISA