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PLoS Pathog 7:1002111
J Mol Neurosci
Kinetic chain integration
folic acidFolic acid, folate, vitamin B9 is used for the treatment of folate deficiency and its complications, and for the treatment of folic acid deficiency associated with liver disease, kidney dialysis,
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The research rationale for a selective NNMT inhibitor is to interrupt exactly that diversion, so the cell keeps more of its NAD+ pool and can run its mitochondrial machinery again
