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482 In lymphoma cells, RNF5 selectively targets the myeloid differentiation primary response protein 88 (MYD88) mutant (L265P), which is common in patients with hematological malignancies, for degradation, likely due to its misfolding

thanks MINECO for a Juan de la Cierva Incorporacion fellowship (IJC2020-045506-I)

Brightening actives reduce dark pigmentation

This effect was associated with reduced serum levels of proinflammatory cytokines including IL-17 and reduced numbers of Th17 cells[251] Therefore, it appears that both curcumin and resveratrol impact two major inflammatory pathways in our current understanding of autoimmune physiology: TH-17 activation and NF-kB activation

Genom 8:11328 [DOI] [PMC free article] [PubMed] [Google Scholar] 107.Chornoguz O, Hagan RS, Haile A, Arwood ML, Gamper CJ, et al

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