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Specifically, HNE reportedly directly activates two members of the stress-activated kinase family, JNK and p38, in NT2 neuronal cells (198)
The innate repair receptor: a multi-level defense system
These structural features are relevant for laboratory interpretation because they reduce some variables that complicate work with cyclic or disulfide-containing peptides, such as incorrect disulfide pairing, oxidative folding state, or multiple disulfide-linked isomers
Nicolas-Boluda, A
doi: 10.1093/nar/gkz850
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