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Compared with 12% of PTEN loss in CM where deletions and mutations both account for the changes ( PTEN is deeply deleted in merely 6.0% of MM cases and has hardly any mutations ( PTEN and amplified KIT that possibly implies that loss of PTEN or gain of KIT are redundant for the activation of the PI3K pathway in MM

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doi:10.1016/j.maturitas.2014.07.013

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