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3 In a separate study, athletes given L-Carnitine before strenuous exercise experienced a decrease in exhaustion and cardiac exertion versus athletes given a placebo

It exhibits a high affinity for the muscle enzyme, carnitine acyl transferase, and as such readily converts into propionyl-CoA and free carnitine

doi: 10.1016/j.fertnstert.2011.04.091

The intake of LC lowers the intramitochondrial acetyl-CoA to free CoA ratio, which promotes pyruvate dehydrogenase activity and glucose oxidation

The study found that these patients frequently exhibited low peripheral serotonin levels alongside mitochondrial dysfunction
