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MicroRNA modulation by nutraceuticals includes upregulation of tumorsuppressive miRNAs (e.g., miR16, miR143) and downregulation of oncogenic miRNAs (e.g., miR21)

The results of the correlation analysis were visualized using a chord diagram (Figure 6) and compounds belonging to the classes of amino acid, lipid, and carbohydrate were the most enriched in the changed endogenous metabolites

In addition, inflammatory response increases the permeability of the alveolar walls, leading to the leakage of fluid and cells from the alveoli and the formation of parenchymal lung lesions (Holloway et al., 2018)

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