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AUC0-168 h ranged from 12 757 nmol x h/L to 15 305 nmol x h/L, and Cmax ranged from 964 nmol/L to 120 nmol/L with semaglutide 24 mg

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Monotherapy protocols are commonly initiated at 0.6 mg per week and escalated to a maximum studied dose of 4.5 mg as tolerated

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