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in endogenously expressed TRPM4 HeLa cells, H 2 O 2 induction of both necrosis and apoptosis has been shown (Simon et al., 2010)

meningitidis (Exley et al., 2005), which metabolizes the lactate by at least three lactate dehydrogenases: two membrane-bound flavin mononucleotide-containing lactate dehydrogenases, LldD and LdhD, which catalyze the oxidation of L -lactate and D -lactate, respectively, and a soluble NAD + -dependent D -lactate dehydrogenase, LdhA (Erwin and Gotschlich, 1993, Erwin and Gotschlich, 1996