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In the same vein, studying IGN onset and unfolding in small rodents would help determine if and in which brain regions pools of BDNF and key neurotransmitters, such as dopamine and glutamate, are more severely affected by single or repeated episodes of IGN, and same for the status of the BDNF-specific receptors, TrkB

All experiments were performed using cell lines from the fifth to tenth passage

doi: 10.1016/j.pain.2006.09.016

Transplantation of myelin-deficient shiverer mutant NSCs in SCI showed that both wildtype and mutant NSC transplants prevented atrophic changes in the injured spinal cord and promoted axonal growth, but only wildtype transplants preserved/enhanced myelination and locomotor functional recovery (Yasuda et al., 2011)

Mitochondrial respiratory function was assessed by high-resolution respirometry using oxygraphy in intact and permeabilized cells (Supplementary Fig