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A rise in cortisol levels would result in mood swings

These include aging-related physiological decline, cardiovascular illnesses (such as hypertension and ischemiareperfusion damage), and neurodegenerative diseases (such as Alzheimers and Parkinsons disease) [1,10]

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In addition to its insulin-like effects (insulin being the main anabolic hormone in the body), [21] IGF1 can also regulate cellular DNA synthesis

Intervention For the first 2 months, the subjects were instructed to take oral TA 250 mg twice daily and apply TCC composed of 5% hydroquinone, 0.003% tretinoin, and 1% hydrocortisone (Melanon cream, DONG-A ST, Korea) to the entire face once a day for 8 weeks