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At the base of the microvilli, where clathrin-coated vesicles are clustering 61 , the MYO6/Dab2 complex assumes a role in receptor uptake through clathrin-coated vesicles, which may require MYO6 to perform tethering or holding functions in its dephosphorylated state

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For the hippocampal model, the primary obstacles are establishing direct causal evidence for its role in pain generation and developing testable biomarkers and interventions based on this framework

This suggests that NE-bound NETs have the potential to serve as a platform for activation and formation of intravascular coagulation,7,8 which partly explains why pulmonary embolism usually occurs in critical COVID-19 patients in the intensive care unit (ICU).9 In some critically ill COVID-19 patients, the coexistence of thrombosis and hemorrhage was observed,10 indicating that suppression of NE production by stabilizing neutrophils could be beneficial for either condition

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