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As indicated, although arginine is an essential amino acid, limited quantities can be derived via enzymes of the urea cycle
doi: 10.1159/000085248

Excessive estrogen affects both the thyroid and adrenal functions

No official contraindication exists, as both work through entirely different mechanisms and metabolic pathways

Another interpretation, elephant in the room, could be that higher protein intakes cause more oxidative stress due to the increased deamination and higher urea/ammonia - just a thought.

Figure 4 Hence, there is a need to delve into the potential of probiotics and their derivatives, individually and in combinations, which exhibit promising activities that could be harnessed in the future (Singh and Rao, 2021)
