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The ligands are the thiolate-containing amino acids such as cysteine [16], the di- and tri-(pseudo)peptides belonging to the biochemical pathway of glutathione, the oligomeric glutathione correlates in the plant kingdom known as phytochelatins and some thiols of pharmacological or other practical utility, such as N- acetyl-cysteine (NAC)

doi: 10.1093/pcp/pcg093

Idebenone, a short-chain synthetic benzoquinone analog of CoQ10, was historically evaluated in clinical trials to bypass mitochondrial complex I/II/III defects and scavenge ROS [95]

It was discovered by Russian scientist Professor Vladimir Khavinson in the 1980s

This heritage provides credibility that newer market entrants simply cannot match