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Results from animal models will inform the design of antibodies for use in humans, but only with evaluation under real-world conditions can the impact of, for example, effector functions on antibody prophylaxis or therapy be fully evaluated

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Adverse effects of vitamin E supplementation have been related to vitamin E-induced activity of P450 enzymes, which in turn enhances the degradation efficiency of drugs used to treat cardiovascular diseases, cancer, metabolic diseases, and other diseases