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[1] [3] Tirzepatide functions as a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist

Two facts regarding transketolase make it a diagnostically useful enzyme

The vitamin A derivative all-trans retinoic acid repairs amyloid--induced double-strand breaks in neural cells and in the murine neocortex

30 More lines of evidence come from the increase in double strand breaks (DSBs) that occur following c-Myc overexpression, observed experimentally by an increase in H2AX foci, a variant of histone H2A protein family and biomarker for DSBs
Vitamin D deficiency is particularly prevalent in cirrhotic patients, affecting up to 92% of this population, further highlighting the need for routine supplementation [40]
