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Interestingly, U11, U12, and U13 were induced by all treatments except in cat2 and cat2 gr1 (Figure 4, compare A and B with C and D)

2) Short-term aerobic exercise increases the number of monocytes, neutrophils, and lymphocytes (Alawna et al., 2020), while long-term exercise intervention suppresses the excessive activation of pro-inflammatory M1 macrophages and promotes the proportion of anti-inflammatory M2 macrophages, thus improving chronic low-grade inflammation (Sleijser-Koehorst et al., 2023

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