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It accommodates maintenance dosing research with first loading phases followed by lower maintenance doses

With 80mg total peptide and daily doses ranging from 2 to 8mg, one vial provides between 10 and 40 doses

Chronic effects have not been reported

Lis (2025) describes desensitization protocols for patients who have developed sensitivity to B12 injections

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The symptoms are largely non-severe, and so overdose is therefore not necessarily something that people worry about when taking B12