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This mechanism increases intracellular concentrations of both NAD+ and SAM, two fundamental molecules that regulate cellular energy expenditure, mitochondrial function, and epigenetic modifications

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Acknowledgements This research was supported in part by the National Institute of Health (R01-GM115622, R01-CA250503 and R01-CA268518 to J.W.), the Cancer Prevention & Research Institute of Texas (CPRIT, RP220480 to J.W.), and Michael E

The average improvement in performance was analysed by using Independent-samples t-test, and the improved swimming results and worsened swimming results were analysed by Chi-square test for frequency distributions

doi: 10.1183/09031936.03.00039602 [DOI] [PubMed] [Google Scholar] 87.Blesa S, Cortijo J, Martinez-Losa M, et al