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Analysis of a UPS-targeted CFP in dopaminergic neurons Twenty UA96 ( unc-119(ed3)

doi: 10.1210/jc.2017-01210 52 HjelholtAJCharidemouEGriffinJLPedersenSBGudiksenAPilegaardHet al

Additional staining was conducted using alcian blue (a histochemical method) and periodic acidSchiff (PAS) for detailed histopathological assessment, specifically for epithelial alterations, villus height (VH) to crypt depth (CD) ratio, with the VH/CD ratio calculated by dividing VH by CD (55)

Ethics statement Ethical approval was not required for the studies on humans in accordance with the local legislation and institutional requirements because only commercially available established cell lines were used

An ideal anticancer therapeutic target should meet specific selectivity for cancer growth, exert toxic killing effects in cancer cells, and have few adverse effects in normal tissue cells, and SLC7A11 appears to meet these criteria [236]
