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2015 Aug 6;15:84. PMID: 26242742

This results in an enhanced interaction between MDM2 and p53, as well as increased ubiquitination of p53 in tumor cells

(2024) L-Ergothioneine ameliorates MPTP-induced Parkinsons disease in C57BL/6J mice by activating DJ-1

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In summary, although the two neurons did not die of GPX4 reduction, the study focused on only one point of GPX4 and did not delve into other regulators, indicating that there are other pathways affecting the activity of POMC neurons under obesity conditions (129)

Nevertheless, more research is required to determine the security and efficacy of such strategies in the clinical setting