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Mihovil et al., 2009

10.1016/S0149-2918(03)90096-8

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We aimed to address the following topics in the consensus: (1) clinical manifestations of B12 deficiency (neurological and hematological endpoints), (2) risk groups, (3) causes of B12 deficiency, (4) laboratory diagnosis of B12 deficiency, and (5) treatment and long-term management of the deficiency

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As it is native and stable in human gastric juice for more than 24 h, as a cytoprotection mediator always given alone, it exerts (according to the original cytoprotection concept) its beneficial effects pleiotropically