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Moreover, it is reported that SC therapy for skin rejuvenation could be conducted by an iontophoretic transdermal transport system in animal model (Ueda, 2014)

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Nat Cell Biol 19: 13361347, 2017

1 , 5 While many candidate gene-environmental interactions associated with this phenomena have not been replicated, the fundamental observations of stressors in childhood predisposing to affective episodes later in adulthood are consistent and highly replicable

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doi: 10.1016/j.neurobiolaging.2013.09.030