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a costimulatory molecule is a cell surface molecule other than an antigen receptor or their ligands that is required for an efficient response of lymphocytes to an antigen

Short peptides such as CAQK are also amenable to other routes of administration, such as intranasal delivery

Then FcRn-GST (0.25 g/ml or 2.0 g/mL), biotinylated human or mouse FcRn (Immunitrack) (2.5 g/mL or 0.25 g/mL) were added and incubated for 1 h at RT

10.1007/s00109-008-0426-z 90

de Wispelaere, M

In mice which were immunized in space, IL-17A and IL-22 were induced, resulting in activation of NF-B which is capable of initiating a positive feedback loop by sustaining the release of additional pro-inflammatory cytokines [77]