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Singly-housing animals, which prevents inter-animal coprophagy, reduces beta diversity of the microbiome compared to stressful (chronic subordinate colony) co-housing conditions 72

Translocation of hormone-sensitive lipase and perilipin upon lipolytic stimulation of rat adipocytes
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Regul Toxicol Pharmacol

Chronic conditions typically require 4-8 weeks minimum before significant changes become apparent

Thorough documentation is key
