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The MTHFR gene has been identified to possess 14 common or rare single nucleotide polymorphism that are associated with enzymatic deficiency 14

Cell-Free Protein Synthesis Using Multiply-Primed Rolling Circle Amplification Products

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Personett HA, Kayhart BM, Barreto EF, Tosh P, Dierkhising R, Mara K et al (2019) Renal recovery following liposomal amphotericin B-induced nephrotoxicity

This study establishes a patterned iPSC-derived sensory neuronal circuitry between DRG organoid (DRGO) sensory neurons and muscle intrafusal fibers, offering an improved in vitro model for studying FRDA pathology and investigating potential therapeutic interventions, such as CRISPR/Cas9-mediated removal of trinucleotide expansions in the FXN gene intron