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[PubMed] [Google Scholar] Miller V.M., Lawrence D.A., Mondal T.K., Seegal R.F

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Studies have shown that 1,25(OH)D directly suppresses renin gene transcription in juxtaglomerular cells, thereby reducing angiotensin II levels and mitigating RAAS overactivation (39)

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Animal studies have shown that in the kidneys of mice induced with DN models by streptozotocin and diabetic (db/db) mice, there is an increase in iron content, particularly in the renal tubules