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EVs originate either from plasma membrane protrusions or endosomes, with endosome-derived EVs being extensively studied and engineered

Life Sciences, 76(3), 345357
Dratman, M

These mutations store up and lead to abnormal mitochondrial metabolism and function, triggering apoptosis
Notably, a proteomic approach identified a set of nitrated proteins, including -enolase, H + -transporting ATPase, and peroxiredoxin-2 in the brains of both Mild Cognitive Impairment (MCI) and AD patients [77]
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