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From a therapeutic standpoint, their main opportunity may be combination design: pairing ferroptosis induction with interventions that remodel mitochondrial electron flow or substrate availability, thereby constraining the capacity to regenerate CoQ 10 H 2

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107 LuoM.WuL.ZhangK.WangH.ZhangT.GutierrezL.et al (2018)

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Nat Rev Immunol 5:331342

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The angiogenic balance between proangiogenic and antiangiogenic factors maintains normal angiogenesis (Semela and Dufour, 2004)

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10.1016/j.jmb.2005.11.091

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Contrarily, upon BPC 157 therapy, contracture was rapidly reversed

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