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Chronic inflammation leads to the secretion of cytokines that sustain inflammation and redox stress, inducing mitochondrial DNA (mtDNA) damage (19)

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According to this method, a pool of DNA with a random sequence region attached to a constant chain is constituted by amplification then transcribed to RNA

doi: 10.1016/j.jtemb.2013.08.005 2 BuettnerGRNgCFWangMRodgersVGJSchaferFQ

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Cluster of orthologous groups (COG) analysis was performed using the Functional Analysis Tools of the T-REx pipeline
