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Description
Discussion This study found an improvement in an important core ASD symptom, verbal communication, in non-syndromic ASD children receiving high-dose folinic acid vs placebo, particularly in those participants who were positive for FRAAs

Cho, W.C

They often need to adopt cumbersome dose-escalation approaches based on the minimally-anticipated biological effect level (MABEL) calculated using suboptimal in vitro preclinical assays

The two most clinically advanced candidates are elesclomol (ES) and disulfiram (DSF)

But here is the problem

Brown G
