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In mice, intravenous injection of fluorescently labeled pHLIP-Ku80 () targeted tumors and reduced Ku80 expression

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3-AR activation triggers a cAMP-mediated signalling cascade that activates hormone-sensitive lipase (HSL) and adipose triglyceride lipase (ATGL), the two primary enzymes responsible for triglyceride hydrolysis in adipocytes

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In the central nervous system (CNS), inflammation is initially a protective physiological response, mediated primarily by resident immune cells, microglia, which detect harmful stimuli such as infections or trauma and help maintain cellular homeostasis