Glutathione: Benefits and Supplements
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Onco Targets Ther
2025;19:e0013164
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Replacement of Sec46 by a cysteine or mutation of any of the 3 other amino acids of the catalytic site results in an abrogation or a diminution of GPX4 enzymatic activity [1]
The initiation of the process is catalyzed by the intracellular iron pool, which reacts with hydrogen peroxide and superoxide to produce oxygen-centered radicals
doi: 10.3390/nu14163263
