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Both compounds are predominantly renally excreted with 29% of methylene blue and 26% of hydroxocobalamin excreted at 24 h post-administration [9, 10]

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A birth cohort perspective, which considers how a certain group of people has passed through different stages of life in particular years, will be increasingly important for understanding factors of risk and resilience that may be unique to the groups of people at highest risk for dementia in the coming decades