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Description
In 2026, agent-based and predictive AI systems are reshaping trial workflows from protocol feasibility and site selection to enrollment forecasting and data integrity oversight

35 , e21593

For highly potent cytotoxic drugs that require rapid action (such as microtubule inhibitors and DNA-damaging agents), cleavable designs can maximize therapeutic potential

doi: 10.1038/nm0797-765 120 McTigueDMHornerPJStokesBTGageFH

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Glutaredoxins (Grxs) can reduce disulfides formed in cytosolic proteins under oxidative and nitrosative stress, and GSH recycles oxidized Grxs (Holmgren, 1979, 1976
