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Oxidative stress results from an imbalance between antioxidants and oxidants (i.e., radicals)

A.BrionesP.MontoyaJ.CortesA.EmperadorS.et al

The Journal of Clinical and Aesthetic Dermatology, [online] 15(5), pp.1928

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However, the bioavailability of oral glutathione is relatively low, meaning it may take longer to see noticeable results
In fact, some studies have demonstrated that in individuals with LHON mtDNA mutations exhibit normal energy charge levels or ATP production in lymphocytes and fibroblasts [486,487]