glutathione rapta c Altered DNA Binding and Amplification of Human Breast Cancer Suppressor Gene BRCA1 Induced by a Novel Antitumor Compound, [Ru(η6-p-phenylethacrynate)Cl2(pta)] responsible for keeping cells protected from free Enhanced Delivery of the RAPTA-C
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[DOI] [PMC free article] [PubMed] [Google Scholar] Badwey J
![glutathione rapta c Altered DNA Binding and Amplification of Human Breast Cancer Suppressor Gene BRCA1 Induced by a Novel Antitumor Compound, [Ru(6-p-phenylethacrynate)Cl2(pta)] responsible for keeping cells protected from free Enhanced Delivery of the RAPTA-C](https://pubs.acs.org/cms/10.1021/bm4013919/asset/images/medium/bm-2013-013919_0011.gif)
The targeting process involves multiple steps from initial receptor binding through downstream metabolic effects
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Unfortunately, its susceptibility to enzymatic degradation significantly limits its medical applicability
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Mitochondria may mediate prenatal environmental influences in autism spectrum disorder
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