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Gallbladder-related adverse events, including cholelithiasis and cholecystitis, have been reported with GLP-1 receptor agonist therapy

For statistical comparisons, two-tailed Students t-tests were employed for two-group comparisons, while one-way or two-way ANOVA with Bonferroni correction was used for comparisons involving three or more groups

However, milk thistle has mild CYP3A4 interactions, and any supplementation should be discussed with your provider, especially if you take other medications or have liver disease

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Laparoscopic versus small-incision cholecystectomy for patients with symptomatic cholecystolithiasis